Vitamin E supplementation was protective against the development of various cancers, most notable lung and prostate cancer. Over a number of years, vitamin E succinate (alpha- tocopheryl succinate) has shown the most impressive anti cancer properties compared to all other forms of vitamin E. This form of Vitamin E causes rapid production of reactive oxygen species (free radicals) selectively within cancer cells, triggering cell death, while being nontoxic to normal, healthy cells. Vitamin E succinate also inhibits the anti- apoptotic function of Bcl-2 and Bcl-xl, normally expressed by tumor cells.

Human Studies Underway

The impressive experimental cancer- killing effects of vitamin E succinate, coupled with our understanding of its observed anti- cancer properties (particularly reactive oxygen species- inducedd apoptosis). It may be wise to choose a multivitamin that contains vitamin E in the form of vitamin E succinate at a minimum dose of 400 IU for purposes of health promotion and possibly cancer prevention.